A General Spatio-Temporal Clustering-Based Non-local Formulation for Multiscale Modeling of Compartmentalized Reservoirs

Representing the reservoir as a network of discrete compartments with neighbor and non-neighbor connections is a fast, yet accurate method for analyzing oil and gas reservoirs. Automatic and rapid detection of coarse-scale compartments with distinct static and dynamic properties is an integral part of such high-level reservoir analysis. In this work, we present a hybrid framework specific to reservoir analysis for an automatic detection of clusters in space using spatial and temporal field data, coupled with a physics-based multiscale modeling approach. In this work a novel hybrid approach is presented in which we couple a physics-based non-local modeling framework with data-driven clustering techniques to provide a fast and accurate multiscale modeling of compartmentalized reservoirs. This research also adds to the literature by presenting a comprehensive work on spatio-temporal clustering for reservoir studies applications that well considers the clustering complexities, the intrinsic sparse and noisy nature of the data, and the interpretability of the outcome. Keywords: Artificial Intelligence; Machine Learning; Spatio-Temporal Clustering; Physics-Based Data-Driven Formulation; Multiscale Modelin

Acute Thrombotic Occlusion of proximal Left Anterior Descending Artery without ST-elevation (de Winter sign) in Electrocardiogram: A Case Report

Introduction: ST-elevation in precordial leads is diagnostic for acute transmural myocardial infarction (MI) related to acute occlusion of left anterior descending artery (LAD). Case presentation: In this case report, a 54-year-old man was admitted to the emergency department (ED) due to chest pain. ST-depression with tall T waves in precordial leads was detected in surface electrocardiogram (ECG). Angiography showed acute total occlusion of proximal LAD and ad hoc percutaneous coronary intervention (PCI) was performed successfully. Conclusion: This case highlights that total occlusion of LAD may present without typical ST-elevation pattern in ECG

Cellular Underwater Wireless Optical CDMA Network: Potentials and Challenges

Underwater wireless optical communications is an emerging solution to the expanding demand for broadband links in oceans and seas. In this paper, a cellular underwater wireless optical code division multiple-access (UW-OCDMA) network is proposed to provide broadband links for commercial and military applications. The optical orthogonal codes (OOC) are employed as signature codes of underwater mobile users. Fundamental key aspects of the network such as its backhaul architecture, its potential applications and its design challenges are presented. In particular, the proposed network is used as infrastructure of centralized, decentralized and relay-assisted underwater sensor networks for high-speed real-time monitoring. Furthermore, a promising underwater localization and positioning scheme based on this cellular network is presented. Finally, probable design challenges such as cell edge coverage, blockage avoidance, power control and increasing the network capacity are addressed.Comment: 11 pages, 10 figure

The current advances of CRISPR/Cas-based systems for the detection of COVID-19

The novel coronavirus disease 2019 (COVID-19) still poses a serious threat to every human on the planet nearly 1.5 years after its beginning. Unfortunately, the current diagnostic methods, although highly sensitive and specific, still suffer from many shortcomings. Faster and easy-to-operate diagnostic systems are undoubtedly sorely needed. The CRISPR/Cas platform has gained much attention in recent years in a wide range of biomedical sciences. Besides its treatment potential and drug and vaccine development, it can be used for disease diagnosis. Thus, the CRISPR/Cas-based system holds great promise for providing a rapid and easily deployable COVID-19 detection and is on par with the conventional diagnostic approaches in terms of sensitivity and specificity. In this review article, we discuss the latest advances of CRISPR/Cas technology as a fast and reliable severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection method

Determination of Effect of Oral Vitamin D to Improve Ventilatory Threshold in Healthy Young Adults with Vitamin D Deficiency

Background: Many studies have shown a high prevalence of vitamin D deficiency in different communities. Due to multiple roles of vitamin D in the body, this study was aimed to determine the effect of oral vitamin D3 on ventilatory threshold-1 in a condition of vitamin D deficiency.Materials and Methods: Recent study performed on 25 healthy young adults with the serum levels of 25 Hydroxyvitamin D3 lower than 20 ng/ml, had referred to the sports medicine clinic of Taleghani Hospital of Tehran, in a one-year period (2016-2017). After primary evaluation, baseline ventilatory threshold-1 were determined by cardiopulmonary exercise testing (CPET). Then persons were treated with 50,000 IU/week of oral vitamin D3 for 8 weeks, and one week after the completion of treatment, ventilator threshold-1 was measured again, similar to the beginning conditions of the study, and its changes were studied.Results: The mean baseline ventilatory threshold-1 of participants before any intervention was 22.46 ± 6.45 (ml/kg/min), and after 8 weeks of treatment by 50000 IU/week of oral vitamin D3, increased to 26.79 ± 5.33 (ml/kg/min) at the end of study, which there was a statistically significant increase in ventilatory threshold-1 (p<0.001).Conclusion: Recent study showed that proper treatment of the vitamin D deficiency, improves ventilatory threshold-1 in healthy young adults

On weighted Adams-Bashforth rules

One class of the linear multistep methods for solving the Cauchy problems of the form $y\u27=F(x,y)$, $y(x_{0})=y_{0}$, contains Adams-Bashforth rules of the form $y_{n+1}=y_{n}+hsum_{i=0}^{k-1} B_i^{(k)} F(x_{n-i},y_{n-i})$, where ${ B_i^{(k)}} _{i = 0}^{k - 1}$ are fixed numbers. In this paper, we propose an idea for weighted type of Adams-Bashforth rules for solving the Cauchy problem for singular differential equations,[A(x)y\u27+B(x)y=G(x,y), quad y(x_0)=y_0,]where $A$ and $B$ are two polynomials determining the well-known classical weight functions in the theory of orthogonal polynomials. Some numerical examples are also included

On weighted Adams-Bashforth rules

One class of the linear multistep methods for solving the Cauchy problems of the form $y\u27=F(x,y)$, $y(x_{0})=y_{0}$, contains Adams-Bashforth rules of the form $y_{n+1}=y_{n}+hsum_{i=0}^{k-1} B_i^{(k)} F(x_{n-i},y_{n-i})$, where ${ B_i^{(k)}} _{i = 0}^{k - 1}$ are fixed numbers. In this paper, we propose an idea for weighted type of Adams-Bashforth rules for solving the Cauchy problem for singular differential equations,[A(x)y\u27+B(x)y=G(x,y), quad y(x_0)=y_0,]where $A$ and $B$ are two polynomials determining the well-known classical weight functions in the theory of orthogonal polynomials. Some numerical examples are also included